Good Anatomical Outcome of Orbital Plasmacytoma Following Chemo-Radiotherapy

Secondary Extramedullary Plasmacytoma of the Orbit
Vol. 12 No. 2 : 2017 (341-347)

Norshamsiah MD
Norshamsiah MD
Othmaliza O
Othmaliza O
KHAIRUNISA AA
KHAIRUNISA AA

Abstract
Extramedullary plasmacytoma is a rare complication from multiple myeloma.We report a 56-year-old lady with underlying multiple myeloma who developed swelling over the left eye. It caused a non-axial proptosis, exposure keratopathy and visual acuity of counting fingers. A tissue biopsy revealed infiltration of tissue fragments with neoplastic plasma cells positive for CD138 and Kappa light chain restrictions consistent with plasmacytoma. Following radio-chemotherapy, the mass shrunk tremendously but her visual outcome remained poor.

Keywords : extramedullary, multiple myeloma, optic nerve injuries, Plasmacytoma, proptosis,

Correspondance Address
Othmaliza Othman. Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia. Tel: +603-91455981 Fax: +603-91456673 E-mail: drlizasaha@yahoo.com