Early Recognition and Intervention of De Winter Syndrome: A Case Report

De Winter Syndrome: Early Recognition & Action
Vol. 20 No. 1 : 2025 (390-397)

Nurhuda Nadzri
Nurhuda Nadzri
Ismail Mohd Saiboon
Ismail Mohd Saiboon

Abstract
De Winter syndrome is a rare but important ST-elevation myocardial infarction (STEMI) equivalent, that is characterised by severe stenosis of the left anterior descending artery (LAD). It can be easily misdiagnosed due to its atypical electrocardiogram (ECG) pattern which causing a delay in reperfusion, hence increases risk of mortality. Herein, we reported a 38-year-old man presented to the emergency department (ED) with initial ECG showed hyperacute T wave, which later evolved to de Winter syndrome ECG pattern after serial ECG were done. He was immediately referred to the cardiology team and underwent immediate percutaneous coronary intervention (PCI) to revascularise the stenosis found at the left anterior descending artery (LAD). He showed good outcomes and no complication after the procedure. This paper aimed to shed light on the importance of early identification, right diagnosis and treatment in De Winter syndrome case to avoid complications.

Keywords : Acute coronary syndrome; de Winter electrocardiogram; LAD occlusion; ST-elevation myocardial infarction equivalent,

Correspondance Address
Professor Dr. Ismail Mohd Saiboon. Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia. Tel: +6019 3200297 Email: fadzmail69@yahoo.com.my